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Article

The Arabidopsis Deubiquitylase OTU5 Suppresses Flowering by Histone Modification-Mediated Activation of the Major Flowering Repressors FLC, MAF4, and MAF5.

International journal of molecular sciences - 24 Mar 2023

Radjacommare Ramalingam, Lin Shih-Yun, Usharani Raju, Lin Wen-Dar, Jauh Guang-Yuh, Schmidt Wolfgang, Fu Hongyong

Abstract excerpt

Distinct phylogeny and substrate specificities suggest that 12 Arabidopsis Ovarian Tumor domain-containing (OTU) deubiquitinases participate in conserved or plant-specific functions. The otu5-1 null mutant displayed a pleiotropic phenotype, including early flowering, mimicking that of mutants harboring defects in subunits (e.g., ARP6) of the SWR1 complex (SWR1c) involved in histone H2A.Z deposition. Transcriptome...

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PMID: 37047144
DOI: 10.3390/ijms24076176
PMCID: PMC10093928

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