Article
Pertuzumab Plus Trastuzumab in Patients With Endometrial Cancer With ERBB2/3 Amplification, Overexpression, or Mutation: Results From the TAPUR Study.
JCO precision oncology - 1 Apr 2023
Ahn Eugene R, Rothe Michael, Mangat Pam K, Garrett-Mayer Elizabeth, Ali-Ahmad Hussein M, Chan John, Maitland Michael L, Patel Sapna R, Reese Zachary, Balmanoukian Ani S, Drescher Charles W, Li Rui, Tsimberidou Apostolia M, Leath Charles A, O'Lone Raegan, Grantham Gina N, Halabi Susan, Schilsky Richard L
Abstract excerpt
PURPOSE: The TAPUR Study is a pragmatic basket trial evaluating antitumor activity of commercially available targeted agents in patients with advanced cancers harboring potentially actionable genomic alterations. Data from a cohort of patients with endometrial cancer (EC) with ERBB2 or ERBB3 (ERBB2/3) amplification, overexpression, or mutation treated with pertuzumab plus trastuzumab (P + T) are reported....
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