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Pertuzumab Plus Trastuzumab in Patients With Colorectal Cancer With ERBB2 Amplification or ERBB2/3 Mutations: Results From the TAPUR Study.

JCO precision oncology - 1 Oct 2022

Gupta Ranju, Meric-Bernstam Funda, Rothe Michael, Garrett-Mayer Elizabeth, Mangat Pam K, D'Andre Stacy, Ahn Eugene R, O'Lone Raegan, Halabi Susan, Grantham Gina N, Schilsky Richard L

Abstract excerpt

PURPOSE: The TAPUR Study is a pragmatic phase II basket trial evaluating antitumor activity of commercially available targeted agents in patients with advanced cancers harboring potentially actionable genomic alterations. Data from two cohorts of patients with colorectal cancer (CRC) with either ERBB2 amplifications or ERBB2 or ERBB3 (ERBB2/3) mutations treated with pertuzumab plus trastuzumab (P + T) are...

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PMID: 36315917
DOI: 10.1200/PO.22.00306

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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