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Article

Effect of COP1 in Promoting the Tumorigenesis of Gastric Cancer by Down‐Regulation of CDH18 via PI3K/AKT Signal Pathway

1 Jan 2023

Abstract excerpt

In recent years, the involvement of E3 ubiquitin ligase constitutive photomorphogenesis 1 (COP1) in the tumorigenesis of gastric cancer (GC) has been elucidated. However, the exact underlying mechanism remains to be clarified. In the present study, the expression profiles of COP1 in GC were derived from the Gene Expression Omnibus (GEO) and the Cancer Genome Atlas (TCGA) databases, followed by verification via...

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PMID: 37025097
DOI: 10.1155/2023/5617875

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