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Article

Text mining of CHO bioprocess bibliome: Topic modeling and document classification.

PloS one - 1 Jan 2023

Wang Qinghua, Olshin Jonathan, Vijay-Shanker K, Wu Cathy H

Abstract excerpt

Chinese hamster ovary (CHO) cells are widely used for mass production of therapeutic proteins in the pharmaceutical industry. With the growing need in optimizing the performance of producer CHO cell lines, research on CHO cell line development and bioprocess continues to increase in recent decades. Bibliographic mapping and classification of relevant research studies will be essential for identifying research...

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Identifiers

PMID: 37022994
DOI: 10.1371/journal.pone.0274042
PMCID: PMC10079098

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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