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N′-Phenylacetohydrazide Derivatives as Potent Ebola Virus Entry Inhibitors with an Improved Pharmacokinetic Profile

6 Apr 2023

Abstract excerpt

High Resolution Image Download MS PowerPoint Slide Ebola virus (EBOV) is a single-strand RNA virus belonging to the Filoviridae family, which has been associated to most Ebola virus disease outbreaks to date, including the West African and the North Kivu epidemics between 2013 and 2022. This unprecedented health emergency prompted the search for effective medical countermeasures. Following up on the carbazole hit...

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PMID: 37021830
DOI: 10.1021/acs.jmedchem.2c01785

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