Article
Discrimination of the chemotherapy resistance status of human leukemia and glioblastoma cell lines by MALDI-TOF-MS profiling.
Scientific reports - 5 Apr 2023
Ledesma Martín, Poodts Daniela, Amoia Sofía, Hajos Silvia, Fundia Ariela, Vay Carlos, Pibuel Matías, Lompardía Silvina
Abstract excerpt
Chemotherapy mistreatment is partially due to a lack of rapid and reliable tools to discriminate between sensitive and resistant phenotypes. In many cases, the resistance mechanism is not fully understood, contributing to the diagnostic tools' absence. This work aims to determine the capacity of MALDI-TOF-MS profiling to discriminate between chemotherapy-resistant and sensitive phenotypes in leukemia and...
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