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Genetic polymorphisms rs1800871 and rs1800872 of IL-10 gene are associated with dengue infection, especially with serotype 1 and DwoWS in Mexican population.

Cytokine - 1 Jun 2023

Eloisa Monroy-Muñoz Irma, Esteban Muñoz-Medina José, Manuel Fragoso José, Esperanza Santacruz-Tinoco Clara, Sevilla-Montoya Rosalba, Hidalgo-Bravo Alberto, Montes-Herrera Daniel, Bravo-Flores Eyerahi, Angeles-Martínez Javier

Abstract excerpt

INTRODUCTION: Dengue infection is generated by a complex interaction between DENV (Dengue Virus) and the host's immune response. Interleukin-10 is an immunoregulatory cytokine during DENV infection. The objective of this study was to investigate whether genetic variants in IL-10 could be useful as a predictive and susceptibility marker in the prognosis of DENV infection, particularly with serotype 1, and in...

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PMID: 37015157
DOI: 10.1016/j.cyto.2023.156194

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