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Cellular senescence and the blood–brain barrier: Implications for aging and age-related diseases

1 Mar 2023

Abstract excerpt

The blood–brain barrier (BBB) is a critical physiochemical interface that regulates communication between the brain and blood. It is comprised of brain endothelial cells which regulate the BBB’s barrier and interface properties and is surrounded by supportive brain cell types including pericytes and astrocytes. Recent reports have suggested that the BBB undergoes dysfunction during normative aging and in disease....

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PMID: 37012666
DOI: 10.1177/15353702231157917

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