Article
Delay discounting as a behavioral phenotype associated with social rank in female and male cynomolgus monkeys: Correlation with kappa opioid receptor availability.
Pharmacology, biochemistry, and behavior - 1 Apr 2023
Johnson Bernard N, Allen Mia I, Reboussin Beth A, LaValley Christina, Nader Michael A
Abstract excerpt
Cocaine use disorder (CUD) is a significant problem worldwide, with no FDA-approved treatments. Epidemiological data indicate that only about 17 % of people that use cocaine will meet DSM criteria for CUD. Thus, the identification of biomarkers predictive of eventual cocaine use may be of great value. Two potentially useful predictors of CUD are social hierarchies in nonhuman primates and delay discounting. Both...
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