Article
Dissociable effects of kappa-opioid receptor activation on impulsive phenotypes in wistar rats.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Oct 2013
Walker Brendan M, Kissler Jessica L
Abstract excerpt
The kappa-opioid receptor (KOR) is the primary target for the endogenous opioid peptide dynorphin (DYN), and KORs reside within brain circuitry underlying the complex integration of information related to different behavioral domains such as motivation, negative affect, and decision-making. Alterations in extended amygdala DYNs and KOR function following chronic alcohol exposure have been shown to mediate...
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