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Crosstalk between Autophagy and RLR Signaling

21 Mar 2023

Abstract excerpt

Autophagy plays a homeostatic role in regulating cellular metabolism by degrading unwanted intracellular materials and acts as a host defense mechanism by eliminating infecting pathogens, such as viruses. Upon viral infection, host cells often activate retinoic acid-inducible gene I (RIG-I)-like receptor (RLR) signaling to induce the transcription of type I interferons, thus establishing the first line of the...

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PMID: 36980296
DOI: 10.3390/cells12060956

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