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Greater Invasion and Persistence of mcr-1- Bearing Plasmids in Escherichia coli than in Klebsiella pneumoniae

28 Mar 2023

Abstract excerpt

As infections caused by multidrug-resistant “superbugs” are increasing globally, polymyxins are often the only viable therapeutic option. Alarmingly, the wide spread of the plasmid-mediated polymyxin resistance gene mcr-1 is restricting the clinical utility of this last-line treatment option.

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PMID: 36975832
DOI: 10.1128/spectrum.03223-22

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