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Generation of human induced pluripotent stem cell line (BCRTi006-A) from a patient with focal segmental glomerulosclerosis disease.

Stem cell research - 1 Jun 2023

Batool Lilas, Raab Constanze, Beez Christien Madlen, Hariharan Krithika, Kurtz Andreas, Gollasch Maik, Rossbach Bella

Abstract excerpt

Individuals with transient reception potential cation channel 6 (TRPC6) mutation have variable phenotypes, ranging from healthy carriers to focal segmental glomerulosclerosis (FSGS). Human induced pluripotent stem cell (hiPSC) line was generated from the urinary cells of a patient with FSGS with a mutant variant of TRPC6. The cells were reprogrammed with Yamanaka factors (OCT3, SOX2, LIN28, L-MYC, and KLF4) using...

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Cell Differentiation
Cellular Reprogramming
Glomerulosclerosis, Focal Segmental
Induced Pluripotent Stem Cells
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pluripotent Stem Cells

TRPC6 Cation Channel

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Identifiers

PMID: 36958215
DOI: 10.1016/j.scr.2023.103070

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Generation of human induced pluripotent stem cell line (BCRTi006-A) from a patient with focal segmental glomerulosclerosis disease.PMID 36958215Read ↗

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