Article
A generation of human induced pluripotent stem cell line (MUi031-A) from a type-3 Gaucher disease patient carrying homozygous mutation on GBA1 gene.
Stem cell research - 1 Apr 2022
Pornsukjantra Tanapat, Kangboonruang Kitsada, Tong-Ngam Pirut, Tim-Aroon Thipwimol, Wattanasirichaigoon Duangrurdee, Anurathapan Usanarat, Hongeng Suradej, Tubsuwan Alisa, Bhukhai Kanit, Asavapanumas Nithi
Abstract excerpt
Gaucher disease (GD) is one of the most prevalent lysosomal storage diseases caused by mutation of glucocerebrosidase (GBA1) gene. GD patients develop symptoms in various organs of the body; however, the underlying mechanisms causing pathology are still elusive. Thus, a suitable disease model is important in order to facilitate subsequent investigations. Here, we established MUi031-A human induced pluripotent...
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