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Amplification-Free COVID-19 Detection by Digital Droplet REVEALR

22 Mar 2023

Abstract excerpt

The COVID-19 pandemic, caused by the SARS-CoV-2 virus, exposed a pressing need for new public health tools for pathogen detection, disease diagnosis, and viral genotyping. REVEALR (RNA-encoded viral nucleic acid analyte reporter) is an isothermal DNAzyme-based point-of-care diagnostic that functions with a detection limit of ∼10 copies/μL when coupled with a preamplification step and can be utilized for viral...

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PMID: 36947677
DOI: 10.1021/acssynbio.3c00105

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