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Impact of multifocal or multicentric disease on local recurrence and survival in breast cancer patients with or without BRCA1/2 variants.

Breast cancer research and treatment - 1 May 2023

Liu Xuejing, Wang Yanjie, Cao Kun, Yao Lu, Hu Li, Sun Jie, Zhang Juan, Xu Ye, Xie Yuntao

Abstract excerpt

PURPOSE: Multifocal or multicentric (MFMC) breast cancer is mainly focused on breast cancer patients with unknown BRCA status, the incidence and clinical relevance of MFMC disease in BRCA1/2 carriers is less explored to date. Our study was to investigate the incidence of MFMC disease in BRCA1/2 carriers and whether MFMC disease influences local recurrence and clinical outcomes. METHODS: In this retrospective...

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PMID: 36930346
DOI: 10.1007/s10549-023-06904-4

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