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Article

Multifocal breast cancers are more prevalent in BRCA2 versus BRCA1 mutation carriers.

The journal of pathology. Clinical research - 1 Apr 2020

McCrorie Alan D, Ashfield Susannah, Begley Aislinn, Mcilmunn Colin, Morrison Patrick J, Boyd Clinton, Eccles Bryony, Greville-Heygate Stephanie, Copson Ellen R, Cutress Ramsey I, Eccles Diana M, Savage Kienan I, McIntosh Stuart A

Abstract excerpt

Multifocal (MF)/multicentric (MC) breast cancer is generally considered to be where two or more breast tumours are present within the same breast, and is seen in ~10% of breast cancer cases. This study investigates the prevalence of multifocality/multicentricity in a cohort of BRCA1/2 mutation carriers with breast cancer from Northern Ireland via cross-sectional analysis. Data from 211 women with BRCA1/2...

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Identifiers

PMID: 32022473
DOI: 10.1002/cjp2.155
PMCID: PMC7164372

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