Article
Enrichment of self-domestication and neural crest function loci in the heritability of neurodevelopmental disorders.
Human genetics - 1 Aug 2023
Koller Dora, Benítez-Burraco Antonio, Polimanti Renato
Abstract excerpt
Self-domestication could contribute to shaping the biology of human brain and consequently the predisposition to neurodevelopmental disorders. Leveraging genome-wide data from the Psychiatric Genomics Consortium, we tested the enrichment of self-domestication and neural crest function loci with respect to the heritability of autism spectrum disorder, schizophrenia (SCZ in East Asian and European ancestries, EAS...
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