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Article

SARS-CoV-2 receptor-binding domain deep mutational AlphaFold2 structures.

Scientific data - 14 Mar 2023

Kilim Oz, Mentes Anikó, Pál Balázs, Csabai István, Gellért Ákos

Abstract excerpt

Leveraging recent advances in computational modeling of proteins with AlphaFold2 (AF2) we provide a complete curated data set of all single mutations from each of the 7 main SARS-CoV-2 lineages spike protein receptor binding domain (RBD) resulting in 3819X7 = 26733 PDB structures. We visualize the generated structures and show that AF2 pLDDT values are correlated with state-of-the-art disorder approximations,...

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PMID: 36918581
DOI: 10.1038/s41597-023-02035-z
PMCID: PMC10013278

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