Article
Experimental evidence for the functional importance and adaptive advantage of A-to-I RNA editing in fungi.
Proceedings of the National Academy of Sciences of the United States of America - 21 Mar 2023
Xin Kaiyun, Zhang Yang, Fan Ligang, Qi Zhaomei, Feng Chanjing, Wang Qinhu, Jiang Cong, Xu Jin-Rong, Liu Huiquan
Abstract excerpt
Adenosine-to-inosine (A-to-I) editing is the most prevalent type of RNA editing in animals, and it occurs in fungi specifically during sexual reproduction. However, it is debatable whether A-to-I RNA editing is adaptive. Deciphering the functional importance of individual editing sites is essential for the mechanistic understanding of the adaptive advantages of RNA editing. Here, by performing gene deletion for...
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