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Article

Autoantibodies against complement factor B in rheumatoid arthritis

20 Feb 2023

Abstract excerpt

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disorder affecting the joints. Many patients carry anti-citrullinated protein autoantibodies (ACPA). Overactivation of the complement system seems to be part of the pathogenesis of RA, and autoantibodies against the pathway initiators C1q and MBL, and the regulator of the complement alternative pathway, factor H (FH), were previously reported. Our aim...

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Identifiers

PMID: 36891314
DOI: 10.3389/fimmu.2023.1113015

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