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Article

Identification of potential therapeutic intervening targets by in-silico analysis of nsSNPs in preterm birth-related genes.

PloS one - 1 Jan 2023

Azmi Muhammad Bilal, Khan Waqasuddin, Azim M Kamran, Nisar Muhammad Imran, Jehan Fyezah

Abstract excerpt

Prematurity is the foremost cause of death in children under 5 years of age. Genetics contributes to 25-40% of all preterm births (PTB) yet we still need to identify specific targets for intervention based on genetic pathways. This study involved the effect of region-specific non-synonymous variations and their transcript level mutational impact on protein functioning and stability by various in-silico tools....

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Source

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Identifiers

PMID: 36881567
DOI: 10.1371/journal.pone.0280305
PMCID: PMC9990928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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