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Article

Proteomic profiling of IgA nephropathy reveals distinct molecular prognostic subtypes

13 Jan 2023

Abstract excerpt

IgA nephropathy (IgAN) is a heterogeneous disease, which poses a series of challenges to accurate diagnosis and personalized therapy. Herein, we constructed a systematic quantitative proteome atlas from 59 IgAN and 19 normal control donors. Consensus sub-clustering of proteomic profiles divided IgAN into three subtypes (IgAN-C1, C2, and C3). IgAN-C2 had similar proteome expression patterns with normal control,...

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PMID: 36879796
DOI: 10.1016/j.isci.2023.105961

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