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Article

Associations of polygenic risk scores with posttraumatic stress symptom trajectories following combat deployment.

Psychological medicine - 1 Oct 2023

Campbell-Sills Laura, Papini Santiago, Norman Sonya B, Choi Karmel W, He Feng, Sun Xiaoying, Kessler Ronald C, Ursano Robert J, Jain Sonia, Stein Murray B

Abstract excerpt

BACKGROUND: Identification of genetic risk factors may inform the prevention and treatment of posttraumatic stress disorder (PTSD). This study evaluates the associations of polygenic risk scores (PRS) with patterns of posttraumatic stress symptoms following combat deployment. METHOD: US Army soldiers of European ancestry (n = 4900) provided genomic data and ratings of posttraumatic stress symptoms before and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36876647
DOI: 10.1017/S0033291723000211
PMCID: PMC10480347

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