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Article

The effect of adjusting LDL-cholesterol for Lp(a)-cholesterol on the diagnosis of familial hypercholesterolaemia.

Journal of clinical lipidology - 1 Jan 2000

Thayabaran Darmiga, Tsui Anson P T, Ebmeier Stefan, Cegla Jaimini, David Alessia, Jones Ben

Abstract excerpt

BACKGROUND: Familial hypercholesterolaemia (FH) diagnostic tools help prioritise patients for genetic testing and include LDL-C estimates commonly calculated using the Friedewald equation. However, cholesterol contributions from lipoprotein(a) (Lp(a)) can overestimate 'true' LDL-C, leading to potentially inappropriate clinical FH diagnosis. OBJECTIVE: To assess how adjusting LDL-C for Lp(a)-cholesterol affects FH...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36870882
DOI: 10.1016/j.jacl.2023.01.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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