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Article

CXCR1: A Cancer Stem Cell Marker and Therapeutic Target in Solid Tumors

16 Feb 2023

Abstract excerpt

Therapy resistance is a significant concern while treating malignant disease. Accumulating evidence suggests that a subset of cancer cells potentiates tumor survival, therapy resistance, and relapse. Several different pathways regulate these purported cancer stem cells (CSCs). Evidence shows that the inflammatory tumor microenvironment plays a crucial role in maintaining the cancer stem cell pool. Typically, in...

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PMID: 36831112
DOI: 10.3390/biomedicines11020576

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