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Whole transcriptome analysis to explore the impaired immunological features in critically ill elderly patients with sepsis

23 Feb 2023

Abstract excerpt

BACKGROUND: Sepsis is a frequent complication in critically ill patients, is highly heterogeneous and is associated with high morbidity and mortality rates, especially in the elderly population. Utilizing RNA sequencing (RNA-Seq) to analyze biological pathways is widely used in clinical and molecular genetic studies, but studies in elderly patients with sepsis are still lacking. Hence, we investigated the...

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Share to Immune Response and Inflammation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36823620
DOI: 10.1186/s12967-023-04002-z

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