Article
An integrated study of hormone-related sarcopenia for modeling and comparative transcriptome in rats
1 Feb 2023
Abstract excerpt
Sarcopenia is a senile disease with high morbidity, serious complications and limited clinical treatments. Menopause increases the risk of sarcopenia in females, while the exact pathogenesis remains unclear. To systematically investigate the development of hormone-related sarcopenia, we established a model of sarcopenia by ovariectomy and recorded successive characteristic changes. Furthermore, we performed the...
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