Experimental Models of Sarcopenia: Bridging Molecular Mechanism and Therapeutic Strategy.

Abstract excerpt

Sarcopenia has been defined as a progressive decline of skeletal muscle mass, strength, and functions in elderly people. It is accompanied by physical frailty, functional disability, falls, hospitalization, and mortality, and is becoming a major geriatric disorder owing to the increasing life expectancy and growing older population worldwide. Experimental models are critical to understand the pathophysiology of...

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• Aging
• Disease Models, Animal
• Mitochondria
• Oxidative Stress
• Phenotype