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Identification of MDK as a Hypoxia- and Epithelial–Mesenchymal Transition-Related Gene Biomarker of Glioblastoma Based on a Novel Risk Model and In Vitro Experiments

1 Jan 2024

Abstract excerpt

Background: Tumor cells are commonly exposed to a hypoxic environment, which can easily induce the epithelial–mesenchymal transition (EMT) of tumor cells, further affecting tumor proliferation, invasion, metastasis, and drug resistance. However, the predictive role of hypoxia and EMT-related genes in glioblastoma (GBM) has not been investigated. Methods: Intersection genes were identified by weighted correlation...

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PMID: 38255198
DOI: 10.3390/biomedicines12010092

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