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Artificial intelligence-based clustering and characterization of Parkinson's disease trajectories

18 Feb 2023

Abstract excerpt

Parkinson's disease (PD) is a highly heterogeneous disease both with respect to arising symptoms and its progression over time. This hampers the design of disease modifying trials for PD as treatments which would potentially show efficacy in specific patient subgroups could be considered ineffective in a heterogeneous trial cohort. Establishing clusters of PD patients based on their progression patterns could...

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PMID: 36801900
DOI: 10.1038/s41598-023-30038-8

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