Article
Association and Interaction of Genetics and Area-Level Socioeconomic Factors on the Prevalence of Type 2 Diabetes and Obesity.
Diabetes care - 1 May 2023
Cromer Sara J, Lakhani Chirag M, Mercader Josep M, Majarian Timothy D, Schroeder Philip, Cole Joanne B, Florez Jose C, Patel Chirag J, Manning Alisa K, Burnett-Bowie Sherri-Ann M, Merino Jordi, Udler Miriam S
Abstract excerpt
OBJECTIVE: Quantify the impact of genetic and socioeconomic factors on risk of type 2 diabetes (T2D) and obesity. RESEARCH DESIGN AND METHODS: Among participants in the Mass General Brigham Biobank (MGBB) and UK Biobank (UKB), we used logistic regression models to calculate cross-sectional odds of T2D and obesity using 1) polygenic risk scores for T2D and BMI and 2) area-level socioeconomic risk (educational...
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