Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Senolytic effect of high intensity interval exercise on human skeletal muscle

8 Feb 2023

Abstract excerpt

p16INK4a expression is a robust biomarker of senescence for stem cells in human tissues. Here we examined the effect of exercise intensity on in vivo senescence in skeletal muscle, using a randomized counter-balanced crossover design. Biopsied vastus lateralis of 9 sedentary men (age 26.1 ± 2.5 y) were assessed before and after a single bout of moderate steady state exercise (SSE, 60% maximal aerobic power) and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetics, Aging, and Longevity in Model Organisms
Share to Muscle Physiology and Disorders
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36779839
DOI: 10.18632/aging.204511

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Senolytic effect of high intensity interval exercise on human skeletal musclePMID 36779839Read ↗

In vivo analysis of γH2AX+ cells in skeletal muscle from aged and obese humansSemantic proximity Read ↗

Regular, Intense Exercise Training as a Healthy Aging Lifestyle Strategy: Preventing DNA Damage, Telomere Shortening and Adverse DNA Methylation Changes Over a LifetimeSemantic proximity Read ↗

Human skeletal muscle satellite cells: aging, oxidative stress and the mitotic clockSemantic proximity Read ↗

Muscle stem cell and physical activity: what point is the debate at?Semantic proximity Read ↗

Proliferation of Multiple Cell Types in the Skeletal Muscle Tissue Elicited by Acute p21 Suppression.Semantic proximity Read ↗

Forty high-intensity interval training sessions blunt exercise-induced changes in the nuclear protein content of PGC-1α and p53 in human skeletal muscleSemantic proximity Read ↗

High‐Intensity interval training reduces transcriptomic age: A randomized controlled trialSemantic proximity Read ↗

Physical Exercise as an Epigenetic ModulatorSemantic proximity Read ↗

Exercise-induced skeletal muscle signaling pathways and human athletic performanceSemantic proximity Read ↗

Human skeletal muscle possesses an epigenetic memory of high-intensity interval trainingSemantic proximity Read ↗

The effects of resistance training on denervated myofibers, senescent cells, and associated protein markers in middle-aged adultsSemantic proximity Read ↗

Antioxidant supplementation blunts the proteome response to three weeks of sprint interval training preferentially in human type 2 muscle fibresSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.