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Article

Psychological distress and decision-making factors for prophylactic bilateral mastectomy in cancer-unaffected BRCA1/2 pathogenic variant carriers.

Psycho-oncology - 1 Apr 2023

Isselhard Anna, Tüchler Anja, Dick Julia, Scherer Anne, Aue Viktoria, Schmutzler Rita K, Rhiem Kerstin

Abstract excerpt

OBJECTIVE: Women carrying a BRCA1/2 pathogenic variant have an increased risk for breast cancer and may opt for risk-reducing bilateral mastectomy. In this study, we examine which demographic, psychosocial, and personality factors are associated with their decision to undergo risk-reducing bilateral mastectomy. METHODS: Cancer-unaffected women with a pathogenic variant in BRCA1 or BRCA2 were recruited before...

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PMID: 36774644
DOI: 10.1002/pon.6111

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