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Article

Multiplexed target enrichment of coding and non-coding transcriptomes enables studying Candida spp. infections from human derived samples.

Frontiers in cellular and infection microbiology - 1 Jan 2023

Hovhannisyan Hrant, Rodríguez Antonio, Saus Ester, Vaneechoutte Mario, Gabaldón Toni

Abstract excerpt

The study of transcriptomic interactions between host and pathogens in in vivo conditions is challenged by the low relative amounts of the pathogen RNA. Yeast opportunistic pathogens of the genus Candida can cause life-threatening systemic infections in immunocompromised patients, and are of growing medical concern. Four phylogenetically diverse species account for over 90% of Candida infections, and their...

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PMID: 36761895
DOI: 10.3389/fcimb.2023.1093178
PMCID: PMC9902369

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