In-depth quantitative proteomics analysis revealed C1GALT1 depletion in ECC-1 cells mimics an aggressive endometrial cancer phenotype observed in cancer patients with low C1GALT1 expression.

doi:10.1007/s13402-023-00778-w

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In-depth quantitative proteomics analysis revealed C1GALT1 depletion in ECC-1 cells mimics an aggressive endometrial cancer phenotype observed in cancer patients with low C1GALT1 expression.

Cellular oncology (Dordrecht, Netherlands) - 1 Jun 2023

Montero-Calle Ana, López-Janeiro Álvaro, Mendes Marta L, Perez-Hernandez Daniel, Echevarría Irene, Ruz-Caracuel Ignacio, Heredia-Soto Victoria, Mendiola Marta, Hardisson David, Argüeso Pablo, Peláez-García Alberto, Guzman-Aranguez Ana, Barderas Rodrigo

Abstract excerpt

BACKGROUND: Endometrial cancer (EC) is the most common cancer of the female reproductive organs. Despite the good overall prognosis of most low-grade ECs, FIGO I and FIGO II patients might experience tumor recurrence and worse prognosis. The study of alterations related to EC pathogenesis might help to get insights into underlying mechanisms involved in EC development and progression. METHODS: Core tumoral...

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Identifiers

PMID: 36745330
DOI: 10.1007/s13402-023-00778-w
PMCID: PMC10205863

Genes

C1GALT1
ANXA1
LGALS3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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