Article
Association of job stress, FK506 binding protein 51 (FKBP5) gene polymorphisms and their interaction with sleep disturbance.
PeerJ - 1 Jan 2023
Li Peixin, Wang Yuxi, Liu Baoying, Wu Chuancheng, He Chenzhou, Lv Xuejie, Jiang Yu
Abstract excerpt
Background: Sleep disturbance is an outcome of multiple factors including environmental and genetic influences. Job stress, a complex environmental factor, likely affects sleep quality, significantly reducing the quality of life of workers. Additionally, FK506 binding protein 51 (FKBP5) may be a pathogenic factor for sleep disturbance as it regulates hypothalamic-pituitary-adrenal (HPA) axis activity, where HPA...
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