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Article

Epigenetic profile of Japanese supercentenarians: a cross-sectional study

1 Feb 2023

Abstract excerpt

BACKGROUND: Centenarians and supercentenarians with exceptional longevity are excellent models for research towards improvements of healthy life expectancy. Extensive research regarding the maintenance and reduction of epigenetic age has provided insights into increasing healthy longevity. To this end, we explored the epigenetic signatures reflecting hallmarks of exceptional healthy longevity, including avoidance...

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PMID: 36738748
DOI: 10.1016/s2666-7568(23)00002-8

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