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Article

Effects of CFTR-modulator triple therapy on sinunasal symptoms in children and adults with cystic fibrosis.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery - 1 Jul 2023

Bode Sebastian F N, Rapp Hannes, Lienert Nadine, Appel Heike, Fabricius Dorit

Abstract excerpt

PURPOSE: Sinunasal symptoms and chronic rhinusinutitis are common in patients with cystic fibrosis. Cystic fibrosis transmembrane regulator (CFTR) modulators have led to dramatic improvements of respiratory symptoms and quality of life in patients with cystic fibrosis. This study aims to evaluate subjective and objective sinunasal symptoms after start of CFTR-modulator triple therapy. METHODS: 43 patients...

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Identifiers

PMID: 36738326
DOI: 10.1007/s00405-023-07859-4
PMCID: PMC10219879

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