Article
Cystic Fibrosis Transmembrane Conductance Regulator Modulator Therapy: A Review for the Otolaryngologist.
American journal of rhinology & allergy - 1 Jul 2020
Lee Saangyoung E, Farzal Zainab, Daniels M Leigh Anne, Thorp Brian D, Zanation Adam M, Senior Brent A, Ebert Charles S, Kimple Adam J
Abstract excerpt
BACKGROUND: Cystic fibrosis (CF) is a genetic disease that may result in multiple systemic disorders and potentially fatal severe respiratory compromise. However, the advent of CF transmembrane conductance regulator (CFTR) modulators has changed the management of CF for patients with select mutations. Although clinical trials have highlighted increased pulmonary function and decreased exacerbations as a result of...
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