Porcine epidemic diarrhea virus activates PERK-ROS axis to benefit its replication in Vero E6 cells

Abstract excerpt

Of the three branches of unfolded protein response (UPR) that were reportedly activated by porcine epidemic diarrhea virus (PEDV), PERK is recently shown to act as an upstream regulator of oxidative response of the cells. However, it remains unknown if and how PERK activation during PEDV infection would result in oxidative stress, and whether activation of PERK and its downstream molecules affect PEDV...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Animal Virus Infections Studies
• Share to Endoplasmic Reticulum Stress and Disease
• Share to Viral gastroenteritis research and epidemiology