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Article

Association of current molecular subtypes in urothelial carcinoma with patterns of muscularis propria invasion.

Virchows Archiv : an international journal of pathology - 1 Sept 2021

Haghayeghi Koorosh, Lu Shaolei, Matoso Andres, Schiff Stephen F, Mueller-Leonhard Catrina, Amin Ali

Abstract excerpt

Urothelial carcinoma is subdivided into luminal (L), basal (B), and p53-wild-type (WT) molecular subtypes, with basal and p53-WT groups showing more aggressive course and poor treatment response, respectively. The literature on molecular subtypes of UC includes a mixture of different stages. We investigated the molecular profile and outcome of pure cohort of muscle invasive bladder carcinoma (MIBC) considering...

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PMID: 34218288
DOI: 10.1007/s00428-021-03145-y

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