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Article

Pan-cancer onco-signatures reveal a novel mitochondrial subtype of luminal breast cancer with specific regulators.

Journal of translational medicine - 30 Jan 2023

Simeone Ines, Ceccarelli Michele

Abstract excerpt

BACKGROUND: Somatic alterations in cancer cause dysregulation of signaling pathways that control cell-cycle progression, apoptosis, and cell growth. The effect of individual alterations in these pathways differs between individual tumors and tumor types. Recognizing driver events is a complex task requiring integrating multiple molecular data, including genomics, epigenomics, and functional genomics. A common...

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Identifiers

PMID: 36717859
DOI: 10.1186/s12967-023-03907-z
PMCID: PMC9885701

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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