Article
The Genomic landscape of short tandem repeats across multiple ancestries.
PloS one - 1 Jan 2023
Vijayaraghavan Prashanth, Batalov Sergey, Ding Yan, Sanford Erica, Kingsmore Stephen F, Dimmock David, Hobbs Charlotte, Bainbridge Matthew
Abstract excerpt
Short Tandem Repeats (STRs) have been found to play a role in a myriad of complex traits and genetic diseases. We examined the variability in the lengths of over 850,000 STR loci in 996 children with suspected genetic disorders and 1,178 parents across six separate ancestral groups: Africans, Europeans, East Asians, Admixed Americans, Non-admixed Americans, and Pacific Islanders. For each STR locus we compared...
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