Article
The effect of Drosophila attP40 background on the glomerular organization of Or47b olfactory receptor neurons.
G3 (Bethesda, Md.) - 11 Apr 2023
Duan Qichen, Estrella Rachel, Carson Allison, Chen Yang, Volkan Pelin C
Abstract excerpt
Bacteriophage integrase-directed insertion of transgenic constructs into specific genomic loci has been widely used by Drosophila community. The attP40 landing site located on the second chromosome gained popularity because of its high inducible transgene expression levels. Here, unexpectedly, we found that homozygous attP40 chromosome disrupts normal glomerular organization of Or47b olfactory receptor neuron...
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