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Article

Arenobufagin causes ferroptosis in human gastric cancer cells by increasing rev-erbα expression

8 Nov 2022

Abstract excerpt

Background and aims: Gastric cancer is the fifth most diagnosed malignant tumor worldwide with limited effective chemotherapy. Ferroptosis is a new type of programmed cell death, which is becoming as a novel therapeutic target for tumors. Arenobufagin (ArBu) is a bufadienolide isolated from toad skin and venom, which exhibits broad-spectrum anti-tumor activity. It is unclear whether ArBu causes ferroptosis,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36685074
DOI: 10.1016/j.jtcme.2022.10.007

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