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Article

Upregulated DNA Damage-Linked Biomarkers in Parkinson’s Disease Model Mice

1 Jan 2023

Abstract excerpt

Oxidative stress-induced DNA damage has been considered to constitute a unifying pathogenesis in the development of Parkinson's disease (PD). In the present study, multiple measurement methods were applied to examine the expression of DNA damage markers in the brain of the vesicular monoamine transporter 2 transgenic mice (VMAT2 Lo), a PD animal model. The results demonstrated that mainly in the substantia nigra...

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PMID: 36683340
DOI: 10.1177/17590914231152099

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