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DNA Damage and Parkinson’s Disease

10 Apr 2024

Abstract excerpt

The etiology underlying most sporadic Parkinson's' disease (PD) cases is unknown. Environmental exposures have been suggested as putative causes of the disease. In cell models and in animal studies, certain chemicals can destroy dopaminergic neurons. However, the mechanisms of how these chemicals cause the death of neurons is not understood. Several of these agents are mitochondrial toxins that inhibit the...

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PMID: 38673772
DOI: 10.3390/ijms25084187

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