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Apoptosis in the ovary: molecular mechanisms

10 Feb 2005

Abstract excerpt

Cell death was first described in rabbit ovaries (Graaffian follicles), the phenomenon being called 'chromatolysis' rather than apoptosis. In humans, the ovarian endowment of primordial follicles is established during fetal life. Apoptotic cell death depletes this endowment by at least two-thirds before birth, executed with the help of several players and pathways conserved from worms to humans. To date,...

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Share to Cell death mechanisms and regulation
Share to Ovarian cancer diagnosis and treatment
Share to Reproductive Biology and Fertility

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PMID: 15705959
DOI: 10.1093/humupd/dmi001

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